And lastly, clonidine improves neuraxial opioids and, in combination with fentanyl, interacts in an additive way, that may reduce the dose of every part by 60% for postoperative analgesia. One of the theories about the mechanism of action of clonidine during the management of suffering inside the CNS is https://bookmarkity.com/story19856174/5-easy-facts-about-onolidine-described