To identify polymorphic sites that could be used as biomarkers of Ebola virus passage history. we repeatedly amplified Ebola virus (Kikwit variant) in vitro and in vivo and performed deep sequencing analysis of the complete genomes of the viral subpopulations. We then determined the sites undergoing selection during passage in Vero E6 cells. Four locations within the Ebola virus Kikwi... https://www.hacklinkci.com/