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As opposed to CB2, CB1 receptors are involved to special membrane microdomains, known as “lipid rafts” (LR) that modulate CB1-dependent signaling pathways. The useful partnership between CB1 and LR is influenced by cholesterol content; especially, membrane cholesterol enrichment in both Main and immortalized cell traces lowers the binding to CB1 https://augusta-precious-metals-a54321.blogsvila.com/33147565/getting-my-cannabis-strains-to-work

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